I have a personal interest in antibiotics because I worked on beta-lactams in my days in medicinal chemistry.
Apart from the sheer ingenuity that people have used to synthesise a bewildering array of different types, there is also the fascinating story of their development which is closely associated to the industrial developments of the 19th Century which, in turn, were driven by fundamental changes from a rural to a modern urban society.
Here are the materials to be used as pre-work to the activities in class.
If you are interested, you might like to have a look at these resources.
Brotzu and the discovery of the cephalosporins:
Impact of tuberculosis in the US in the 1800s
- U of Virginia visual: Early Research and Treatment of Tuberculosis in the 19th Century,
- Images from the “forgotten plague” PBS programme: https://www.pbs.org/wgbh/americanexperience/features/plague-gallery/ TB in America: 1895-1954